PARKINSON'S DISEASE NEWS
29th April 2009 - New research
THE ROLE OF IRON IN PARKINSON'S DISEASE
Anemia is largely due to insufficient hemoglobin, which transports oxygen in the blood. The major constituent of hemoglobin is iron. So if there is insufficient iron, there will be a lack of hemoglobin. For more information go to Anemia. Iron is also essential for the formation of L-dopa, whose deficiency causes Parkinson's Disease. The quantity of L-dopa formed rises and falls according to the amount of iron available. So when there is insufficient iron, there will be insufficient L-dopa. So rather than anemia increasing the likelihood of Parkinson's Disease, it is likely that insufficient iron increases the simultaneous likelihood of anemia and Parkinson's Disease. In order to refer to this article on its own click here.
21st April 2009 - New research
RIGHT HAND OR LEFT
HAND PARKINSON'S DISEASE
hand was recorded in each person, as well as any significant
right-left differences in tremor, bradykinesia, and rigidity. Symptoms
dominating on one side occurred in the vast majority (85%) of people with
Parkinson's Disease. The
initial symptoms appeared on the right side in 47% of the right-handed patients,
and on the left side in 38% of the right-handed patients. The initial symptoms
appeared on the left side in 52% of the left-handed patients, and on the right
side in 36% of the left-handed patients. So
Parkinson's Disease is characterised by symptoms being
greater on either the right or left hand side. There was a trend towards symptom onset on the dominant side.
In order to refer to this article on its own
16th April 2009 - New research
They tested their theory on rats. Whilst L-Dopa treatment took place, there were significant reductions in abnormal involuntary movements in the creatine-supplemented group, without any worsening of Parkinson's Disease symptoms. The authors concluded that creatine helps to alleviate the dyskinesia that L-dopa can cause. Creatine can be taken as a supplement. However, it is normally made from substances found in the diet. The main food source is meat. Vegetables do not contain creatine. So vegetarians show lower levels of muscle creatine, which after taking creatine supplements, rise to higher levels than in meat-eaters.
15th April 2009 - New web site
New Young Onset Parkinson's Disease Web Site
13th April 2009 - New research
WELDING AS A CAUSE OF PARKINSON'S DISEASE
In fact the mortality rate in was less than normal. The same was true of Alzheimer's Disease and presenile dementia. Earlier research suggested that welding exposures could predispose people to an earlier onset of Parkinson's Disease. However, there was no evidence of an increased mortality rate associated with welding occupations among men younger than 65, while there was evidence of a lower death rate in Parkinson's disease among men age 65 years and older. The inconsistencies between this research and what was previously assumed might be due to this study only assessing the death rate among welders with Parkinson's Disease rather than the actual prevalence of Parkinson's Disease among welders.
10th April 2009 - New research
The medical literature was assessed for clinical trials of acupuncture for Parkinson's Disease. Three clinical trials using acupuncture showed no effect. Six studies compared the use of acupuncture and conventional drugs against the use of only drugs. Only two out of six of these studies suggested a positive effect of scalp acupuncture. Two further clinical trials tested acupuncture versus no treatment. These studies also suggested beneficial effects of acupuncture. However, the results of the latter two types of trial failed to adequately control for non-specific effects. The authors conclude that the evidence for the effectiveness of acupuncture in treating Parkinson's Disease is unconvincing.
A new study in the Journal of Traditional Chinese Medicine has claimed that acupuncture combined with Madopar (which includes L-dopa) is more effective than Madopar alone. For more information go to the Complete abstract
7th April 2009 - New research
PATIENTS HAVE TROUBLE LYING
These personality traits may be associated with dysfunction of specific brain regions affected by Parkinson's Disease. In the present study, researchers showed that most people with Parkinson's disease are "honest", and that this personality trait might be derived from dysfunction of the prefrontal cortex. People with Parkinson's disease had difficulty making deceptive responses when compared to healthy controls. This difficulty was significantly correlated with reduced function in part of the brain. The results are the first to demonstrate the greater honesty found in people with Parkinson's Disease and that it has a neurobiological basis.
3rd April 2009 - News release
THE MICHAEL J.FOX FOUNDATION FUNDS THREE NEW PROJECTS
The Michael J. Fox Foundation for Parkinsonís Research announced that it would make up to $6.5 million in total funding available under three new research programs : (1) one of them aims at understanding the "clinico-pathological correlates" of Parkinsonís disease using extensive clinical data and postmortem tissue from people with and without Parkinson's Disease. (2) Understanding LRRK2 Biology seeks aims at increasing understanding of the role of the gene LRRK2 in Parkinsonís Disease. (3) Postural Instability and Gait Disorders aims at clarifying the pathophysiology and biological correlates of posture and gait dysfunction. For more information go to the complete News release.
Working out correlates, which is what will be used in the first and third projects, merely means finding out what is associated with the symptoms rather than developing or assessing methods of treatment for Parkinson's Disease. The LRRK2 gene is only unusually associated with Parkinson's Disease, and so would not be relevant to most people with Parkinson's Disease.
INTERVIEW : Michael J.Fox's recent interview on The Oprah Winfrey Show concerning Parkinson's Disease Video INTERVIEW : Michael J.Fox's recent interview on Larry King Live concerning Parkinson's Disease Web site
1st April 2009 - History
PARKINSON'S DISEASE IN
Ma's family left him and went out looking for medication because the disease was still progressing. His son inquired of Zhang about medication for his father. Zhang advocated diaphoresis (sweating) using Fangfeng Tongsheng San, then inducing vomiting, expelling wind, and promoting circulation of qi through herbs, and nourishing by food. After treatment for several months, Ma's condition improved. His feet were not as heavy as before. The tremor was less and he was able to walk and to hold a comb, towel, spoon and chopsticks. This case was recorded over 600 years earlier than those reported by James Parkinson, after whom Parkinson's Disease was eventually named.