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Parkinson's Disease News covers
all significant new research, reports, books, and resources concerning
Parkinson's Disease.
Articles are chosen on the basis
of their medical significance or potential interest. Our overwhelming priority
is the facts, regardless of whether they contradict prevailing views or vested
interests. Analysis and further information are provided
either to explain the background or implications, or to
balance misleading claims. If you notice errors or inadequacies, or dispute what is
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16th April - New research
PREVALENT ESOPHAGEAL SYMPTOMS IN PARKINSON'S DISEASE
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Dysphagia (difficulty in swallowing) is a common problem in people with
Parkinson's Disease. In order to assess the prevalence of dysphagia and
other related symptoms, people with Parkinson's Disease presenting with
dysphagia, odynophagia, heartburn, regurgitation, chest pain, and weight
loss underwent evaluation using high-resolution manometry (HRM).
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The
Most people with Parkinson's Disease (62%) experienced dysphagia
(difficult swallowing), which probably contributed to weight loss in
41% of people because they were unable to eat as much. The
prevalence of other symptoms was heartburn (37%), regurgitation
(31%), chest pain (28%), and odynophagia (painful swallowing) (6%).
Problems in the esophagus were also common. The esophagus is through
which food passes from the mouth to the stomach. The most common
problems were : failure by the esophagus to contract properly
(ineffective esophageal peristalsis) (55%), fragmented contraction
in the esophagus (fragmented peristalsis) (48%), spasms in the
esophagus (DES - diffuse esophageal spasm) (48%), and obstruction of
the exit of the esophagus to the stomach (EGJ outflow obstruction)
(39%). Each of these causes digestive problems.
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Reference : Diseases of the Esophagus [2017] 30
(4) : 1-6 (A.Su, R.Gandhy, C.Barlow, G.Triadafilopoulos) Nature
Biotechnology [2017] Apr 10 [Epub ahead of print]
Complete abstract
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