VIARTIS

 

 

 PARKINSON'S DISEASE NEWS

 

 

 

 

 

Parkinson's Disease News covers all significant new research, reports, books, and resources concerning Parkinson's Disease. Articles are chosen on the basis of their medical significance or potential interest. Our overwhelming priority is the facts, regardless of whether they contradict prevailing views or vested interests. Analysis and further information are provided either to explain the background or implications, or to balance misleading claims. If you notice errors or inadequacies, or dispute what is written, or want to propose articles, please e-mail [email protected].

                                          

 

14th July 2014 - New research

FREQUENT MISDIAGNOSIS OF PARKINSON'S DISEASE

Neurology [2014] Jun 27[Epub ahead of print] (C.H.Adler, T.G.Beach, J.G.Hentz, H.A.Shill, J.N.Caviness, E.Driver-Dunckley, M.N.Sabbagh, L.I.Sue, S.A.Jacobson, C.M.Belden, B.N. Dugger)  Complete abstract

Researchers aimed to determine the diagnostic accuracy of a clinical diagnosis of Parkinson's Disease using neuropathologic diagnosis as the standard. The accuracy of diagnosis was found to be very poor.

Data were used to determine the predictive value of a clinical Parkinson's Disease diagnosis, using two clinical diagnostic confidence levels : PossPD (never treated or not clearly responsive) and ProbPD (responsive to medications).

Using neuropathologic findings of Parkinson's Disease as the standard, this study established a finding of only 26% accuracy for a clinical diagnosis of Parkinson's Disease in untreated patients, 53% accuracy in early Parkinson's Disease of less than five years duration that was responsive to medication, and 85% diagnostic accuracy in Parkinson's Disease of longer duration that was medication-responsive. Clinical variables that improved diagnostic accuracy were medication response, motor fluctuations, dyskinesias, and hyposmia (reduced sense of smell).ic accuracy in Parkinson's Disease of longer duration that was medication-responsive.

This study showed that a clinical diagnosis of Parkinson's Disease identifies people who will have pathologically confirmed Parkinson's Disease with a sensitivity of 88% and specificity of 68%. For more information concerning the diagnosis of Parkinson's Disease go to Diagnosis of Parkinson's Disease For more news go to Parkinson's Disease News.

FOR A PRINTABLE OR WHITE BACKGROUND VERSION OF THIS ARTICLE CLICK HERE

E-MAIL NOTIFICATION : If you would like to be notified by e-mail when any new articles are added to Parkinson's Disease News,  please merely e-mail [email protected] with the message "subscribe".  No form of identity is required.  E-mail addresses are not used for any other purpose.


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
2006-2014  Viartis
 
2015-08-07 21:15:50
 
[email protected]