Cabergoline, which is also known by the brand names Dostinex and Cabaser, was the worst of those dopamine agonists assessed. The likelihood of valvular regurgitation in people with Parkinson's Disease taking Cabergoline was more than six times greater than would otherwise be expected. For a full review of Cabergoline go to the Review of Cabergoline. The dopamine agonist Pergolide, which is also known as Permax, makes valvular regurgitation in people with Parkinson's Disease more than three times more likely. The likelihood of Permax causing valvular regurgitation led to its withdrawal in the U.S. in 2007, but it is still used elsewhere. Other dopamine agonists were not assessed. So it is not known to what extent they are harmful in this respect or if they are harmful at all. For more current news go to Parkinson's Disease News.

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