PARKINSON'S DISEASE NEWS

7th May 2011 - New research

DAYTIME SLEEPINESS TRIPLES THE RISK OF PARKINSON'S DISEASE

Sleep Medicine Reviews [2011] 15 (1) : 41-50 (S.Zoccolella, M.Savarese, P.Lamberti, R.Manni, C.Pacchetti, G. Logroscino) Complete abstract

Recent studies showed that sleep disorders may precede the onset of Parkinson's Disease. Excessive daytime sleepiness has been found to be associated with three times the risk of developing Parkinson's Disease. Available information suggests that sleep disorders may actually be the heralding clinical manifestation for Parkinson's Disease onset. Sleep disorders are also one of the most frequent manifestations of Parkinson's Disease once it has developed.  The incidence of sleep disorders during Parkinson's Disease were found to progressively increase with the duration of Parkinson's Disease. Those factors most related with an increase in sleep disorders in Parkinson's Disease are : older age, male gender, higher dosages of dopaminergic drugs, cognitive impairment and hallucinations.

The researchers do not explain why excessive daytime sleepiness could lead to such an increased risk of Parkinson's Disease. However, it is known that melatonin, which is produced during sleep affects dopamine, the substance whose deficiency causes Parkinson's Disease. For more current news go to Parkinson's Disease News.

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Parkinson's Disease News details all significant new research, news reports, new books, and new resources concerning Parkinson's Disease and those medical disorders that often coincide with Parkinson's Disease. It is compiled from an analysis of  all newly published research, news reports, new clinical trials, all newly published books, and new web sites. A summary and analysis of the new research are provided,  as well as links to the complete abstracts and news reports