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24th October 2009 - New research

GAUCHER'S DISEASE AND PARKINSON'S DISEASE

New England Journal of Medicine [2009] 361 (17) : 1651-1661 (Sidransky et al) Complete abstract

Gaucher's Disease has been found to make Parkinson's Disease five times more likely.  Gaucher's Disease is an inherited metabolic disorder in which harmful quantities of a substance called glucocerebroside can accumulate in the spleen, liver, lungs, bone marrow, and the brain. Glucocerebroside accumulates because
glucocerebrosidase (the chemical that breaks it down) is deficient in Gaucher's Disease. It is named after the French doctor Philippe Gaucher, who originally described it. For more information go to Gaucher's Disease. A lot of people are carriers for Gaucher's Disease without realising it. Around 1 in 100 people are a carrier for Gaucher's Disease. In Ashkenazi Jews as many as 1 in 15 are a carrier. Those people that had Gaucher's Disease and Parkinson's Disease developed Parkinson's Disease at an earlier age, were more likely to have affected relatives, and were more likely to have atypical clinical manifestations. Although it is known what causes Gaucher's Disease, it is not known how that can also cause the symptoms of Parkinson's Disease. For more current news go to Parkinson's Disease News.
                                

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Parkinson's Disease News details all significant new research, news reports, new books, and new resources concerning Parkinson's Disease and those medical disorders that often coincide with Parkinson's Disease. It is compiled from an analysis of  all newly published research, news reports, new clinical trials, all newly published books, and new web sites. A summary and analysis of the new research are provided,  as well as links to the complete abstracts and news reports.

                                    

 

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