PARKINSON'S DISEASE NEWS
31st October 2013 - News release
SENSORY PEN FOR DETECTING PARKINSON'S DISEASE
A means of diagnosing Parkinsonís Disease is being developed by MANUS Neurodynamica using sensory pen technology. It is called thee DiPAR project. The system, combining sensor and computing technology, requires the patient to perform a set of writing tasks, drawing activities or a combination of both. The system records all movements of the pen as well as other parameters such as drawing pressure, plus acceleration and deceleration of movement, to identify patterns that are indicative of specific kinds of neuromotor disorder. The sensory pen can be used by non-specialists with minimal training so that large numbers of people would be able to be screened.
The systemís software records key features regarding the movement of the pen, relating it to the motion of the limb, particularly the role of the hand and fingers in coordinating overall pen motion. The recordings enable the operator to assess akinesia, bradykinesia, tremor, rigidity and other signs of motor deterioration that cannot be easily detected by other means. The software takes inputs from a variety of sensors in the pen and converts them, using proprietary algorithms, into outcome percentages that represent the likelihood of the presence of Parkinson's Disease or other neuromotor disorders. The method can be viewed in this brief video video of sensory pen technology In order to refer to this article on its own click here.
13th October 2013 - New research
THE LONG TERM EFFECT OF DBS ON PARKINSON'S DISEASE
Journal of the Formosan Medical Association  Oct 5
[Epub ahead of print] (J.L.Jiang,
S.Y.Chen, T.C.Hsieh, C.W.Lee, S.H.Lin, S.T.Tsai)
The aim of this study was to assess the improvements that can be expected after 1 year and after 5 years. Patients with Parkinson's Disease were assessed after 1 year and 5 years according to the Unified Parkinson's disease rating scale (UPDRS) parts I, II, III, and IV scores, the Hoehn and Yahr stage, and Schwab and England activities of daily living (SEADL) scores in the conditions of off-medication/on-stimulation and off-medication/off-stimulation. Further analysis included the changes in the L-dopa equivalent daily dose.
After 1 year significant improvements were seen in the UPDRS parts I, II, III, and IV and the Schwab and England scale. Five years after STN-DBS had been initiated improvements in UPDRS scores were observed only for parts II, III, and IV. In the off-medication/off-stimulation condition no significant improvement was observed. However, after 5 years there were significant deteriorations when compared to the improvements seen after 1 year in the scores for the UPDRS parts I, II, III and the Schwab and England scale.. Therefore, after the improvement experienced after 1 year the long term trend is downwards. For a printable version of this article click here. In order to refer to this article on its own click here.
7th October 2013 - New research
DUAL LAYER L-DOPA CLINICAL TRIAL RESULTS
Parkinsonism Related Disorders  Sep 5 [Epub ahead of print]
(R.Pahwa, K.E.Lyons, R.A.Hauser, S.Fahn, J.Jankovic, E.Pourcher, A.Hsu,
M.O'Connell, S.Kell, S.Gupta)
All three dosages improved Parkinson's Disease, with the 145mg dosage, then the 245mg dosage giving better results. The most commonly reported adverse events with IPX066 included nausea, dizziness, and headache. No unexpected drug-related serious adverse events were reported. For a printable version of this article click here. In order to refer to this article on its own click here.
3rd October 2013 - New research
DEPRESSION TREBLES THE RISK OF PARKINSON'S DISEASE
Neurology  Oct 2 [Epub ahead of print] (Cheng-Che Shen, Shih-Jen
Tsai, Chin-Lin Perng, Benjamin Ing-Tiau Kuo, Albert C.Yang)
Parkinson's Disease is primarily due to the insufficient formation of dopamine in the brain, in the dopaminergic neurons. Besides affecting muscle function and therefore the characteristic muscular symptoms of Parkinson's Disease such as as rigidity and tremor, dopamine insuffiency also affects the emotions.
This is why dopamine insufficiency can also lead to depression. However, even biochemically, dopamine is not the only factor involved in depression, which is why depresssion and Parkinson's Disease do not always coincide. Therefore, depression, even when severe, does not inevitably lead to Parkinson's Disease and why it is possible to have Parkinson's Disease without also having depression.. For a printable version of this article click here. In order to refer to this article on its own click here.
3rd October 2013 - New book
UNDERSTANDING PARKINSON'S DISEASE : AN INTRODUCTION FOR PATIENTS AND CAREGIVERS
Publisher's description : Understanding Parkinsonís Disease offers patients and their caregivers the kind of cutting-edge information that will allow them to successfully confront this debilitating disease on a number of fronts. Patients will also be uniquely exposed to alternative approaches to managing the symptoms of the disease, including allopathic, osteopathic, and naturopathic approaches. The reader will be introduced to essential information on the risk factors associated with Parkinsonís, the signs and symptoms, the different stages of the disease, the various treatments, as well as how the disease develops. Anyone looking for an introduction will find the information they need in this accessible resource. Click here for more details. For more books concerning Parkinson's Disease go to Parkinson's Disease Books.