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GENETIC CAUSES OF PARKINSON'S DISEASE

 

 

 

 

 

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GENETIC CAUSES

A small proportion of cases of Parkinson's Disease have a genetic cause. Most genetic causes make Parkinson's Disease more likely rather than make it inevitable. Genetic disorders normally occur due to inheritance, either autosomal recessive (from both parents) or autosomal dominant (from one parent), but can arise spontaneously. Having relatives with Parkinson's Disease does not mean that it has been inherited. Relatives can have similar environmental factors as each other that causes their Parkinson's Disease. Most but not all genetic causes are identified by a PARK number.


PARK 1 (Alpha-Synuclein)   GENE SUMMARY Tyrosine Hydroxylase   GENE SUMMARY
   
PARK 2 (Parkin)   GENE SUMMARY Dopa decarboxylase   GENE SUMMARY
   
PARK 3 (Lewy body)   GENE SUMMARY ADORA1   GENE SUMMARY
   
PARK 5 (UCHL1)   GENE SUMMARY CYP2D6   GENE SUMMARY
   
PARK 6 (Pink 1)   GENE SUMMARY DRD2   GENE SUMMARY
   
PARK 7 (DJ-1)   GENE SUMMARY DRD3   GENE SUMMARY
   
PARK 8 (LRRK2)   GENE SUMMARY GLIS1   GENE SUMMARY
   
PARK 9 (ATP13A2)   GENE SUMMARY HLA   GENE SUMMARY
   
PARK 10 (USP24)   GENE SUMMARY LINGO1   GENE SUMMARY
   
PARK 11 (GIGYF2)   GENE SUMMARY MAPT   GENE SUMMARY
   
PARK 12   GENE SUMMARY MCCC1   GENE SUMMARY
PARK 13 (HtrA2)   GENE SUMMARY NR4A2   GENE SUMMARY
   
PARK 14 (PLA2G6)   GENE SUMMARY PDE8B   GENE SUMMARY
   
PARK 15 (FBXO7)   GENE SUMMARY PITX3   GENE SUMMARY
   
PARK 16   GENE SUMMARY PTRHD1   GENE SUMMARY
   
PARK 17 (VPS35)   GENE SUMMARY RAB39B   GENE SUMMARY
   
PARK 18 (EIF4G1)   GENE SUMMARY RIT2   GENE SUMMARY
   
PARK 19 (DNAJC6)   GENE SUMMARY STH   GENE SUMMARY
   
PARK 20 (SYNJ1)   GENE SUMMARY TMEM230   GENE SUMMARY
   
PARK 21 (DNAJC13)   GENE SUMMARY  
   
PARK 22 (CHCHD2)   GENE SUMMARY  
PARK 23 (VPS13C)   GENE SUMMARY  


 

THE COMPREHENSIVE GUIDE TO PARKINSON'S DISEASE

Keith Bridgeman, Tahira Arsham


The Comprehensive Guide to Parkinson's Disease, which is fully referenced, and nearly 800 pages long, is the most comprehensive book concerning Parkinson's Disease ever written. It includes its history, famous people with Parkinson's Disease, its complete biochemisty, cytology and cytological effects, anatomy and anatomical effects, physiology and physiological effects, symptoms (of every system in the body), diagnosis methods (observational, technological, chemical), biochemical causes, toxic causes, genetic causes, pharmacological causes, medical causes, treatments (biochemical, pharmacological, surgical, natural, exercise methods, technological methods), organisations, web sites, nursing.
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